The neurocognitive profile of post-ischemic stroke patients

Abstract

The highest risk of developing depression, anxiety, memory disorders, perception, executive functions, attention and thinking is observed in the first 6 months after ischemic stroke, therefore, the patient's quality of life and the prognosis of the disease will depend on the timely diagnosis of cognitive and psychological disorders.
The aim of the study: to investigate the features of neurocognitive disorders of post-ischemic stroke, which will have practical significance in the form of further optimization of treatment.
78 post-ischemic stroke patients were examined. The average age of the patients was 63.6±5.3 years. The examination was carried out 3 months after the onset. The control group consisted of 27 almost healthy individuals with an average age of 57,3±3.4 years. The modified Rankin Scale (mRS), the Montreal Cognitive Assessment (MoCA), the Frontal Assessment Battery (FAB) and the Hamilton Anxiety Scale (HAM-A) were used to assess the neurocognitive profile.
Patients with moderate and severe functional disorders according to mRS accounted for 74.4%. According to the MoCA scale, less pronounced disorders of attention, orientation, and recognition were observed, compared with the control group (p˂0.01). According to the results of testing using the FAB scale, the most significant differences were established in the subtests “mental flexibility and verbal fluency”, “programming and motor actions”, “sensitivity and obstacles” compared with the control group (p˂0.0001), which correlated with an increased level of anxiety according to the HAM-A scale.
1. The results of a study of patients who had suffered an ischemic stroke and were in the recovery period showed signs of damage to the pyramidal system in the majority of patients (60.3%), which was accompanied by motor deficits and correlated with the assessment data on the modified Rankin scale. 2. The average and above average degree of functional disorders correlated with neurocognitive disorders and a fairly high level of anxiety (34.6%).