Surgical prevention of pulmonary embolism in patients with lower extremities' decompensated chronic venous insufficiency

Authors

  • Viacheslav Vasylovych Korsak SU "Uzhhorod National University"
  • Oleksandr Mykhailovych Kochmar SU “Uzhhorod National University”
  • Fedir Viktorovych Horlenko SU “Uzhhorod National University”
  • Yaroslav Mykhailovych Popovych SU “Uzhhorod National University”

DOI:

https://doi.org/10.32782/2415-8127.2023.68.10

Keywords:

acute varicothrombophlebitis, postthromboitic syndrome, chronic venous insufficiency, open trophic ulcer, pulmonary embolism, surgical prevention

Abstract

Introduction. Allocation into a separate group of patients with embolo-threatening (floating) thrombi has important practical significance for determination to the tactics of surgical treatment, establish the expediency and urgency of surgical intervention. According to European recommendations, the main method of treatment of acute varicothrombophlebitis (AVT) is the appointment of anticoagulant therapy. In the absence of ultrasound control, the patient's non-compliance with medical recommendations, economic difficulties in a particular patient – surgical methods of treatment are offered. The aim of the study. To improve the results of surgical treatment of patients with acute varicothrombophlebitis against the background of venous blood flow decompensation and minimize the possibility of spreading thrombosis to deep veins and the occurrence of pulmonary embolism (PE). Materials and methods. An analysis of the surgical treatment of 104 patients with AVT on the background of decompensated chronic venous insufficiency corresponding to class C6 according to the CEAP classification was carried out. Patients were divided into two groups. In 60 patients of group I, the cause of decompensated chronic venous insufficiency was varicose veins of the lower extremities. 44 patients of the II group were diagnosed with post-thrombotic syndrome of femoro-popliteo-tibial localization in the stage of incomplete recanalization. All patients of both groups were operated on for AVT of great and small subcutaneous veins systems. Results and discussion. The transition of the thrombotic process from superficial to deep veins was detected in 28 (26.9%) patients, namely: in the I group are 12 (20.0%), and in the II group are 16 (36.4%) patients. This indicates a sufficiently significant percentage of patients with a seriously complicated course of decompensated chronic venous insufficiency. Thrombectomy from the femoral and external iliac veins was performed in 8 patients of the I group and 6 patients of the II group. This surgical intervention requires full visual control of the mouth of the great saphenous vein and exposure of the femoral vein sufficient to block blood flow through it. A floating thrombus in the popliteal vein was detected in 14 (13.5%) patients: 4 from the I group and 10 from the II group. All patients underwent urgent radical phlebectomy of the small saphenous vein with removal of floating blood clots from the popliteal vein. After removal of floating thrombi and removal of thrombosed veins on the thigh and lower leg, comprehensive conservative treatment of trophic ulcers was applied, which included: various multicomponent bandages, various types of necrotomy, vacuum therapy, autodermoplasty. In a year, trophic ulcers were healed in all patients of the first group, and in 97.7% of patients of the second group. During the entire observation period of the patients, no cases of PE were registered. Conclusions. 1. Acute superficial thrombophlebitis is a frequent complication of varicose veins and post-thrombophlebitic syndrome and accounts for 40% of patients with venous pathology operated on in a hospital. 2. The dangerous floating nature of blood clots in the system of the small saphenous vein in patients with acute superficial thrombophlebitis against the background of postthrombophlebitic syndrome occurs almost 3.4 times more often than in varicose veins (22.7% compared to 6.7%). Which should prompt a more thorough ultrasound examination of such patients. 3. Complex radical surgical treatment of AVTF allowed reliable prevention of PE and contributed to rapid healing of trophic wounds.

References

Chernukha L. M., Shchukin S. P. Trombotychni uskladnennia vazhkykh form varykoznoi khvoroby: khirurhichne likuvannia ta profilaktyka tromboembolii lehenevoi arterii. Naukovyi visnyk Uzhhorodskoho universytetu. Seriia Medytsyna. 2012, 45(3): 128–132.

Chernukha L. M., Shchukin S. P. Trombotychni uskladnennia tiazhkykh form varykoznoi khvoroby: diahnostyka, khirurhichne likuvannia z zastosuvanniam miniinvazyvnykh metodiv. Klin. khirurhiia. 2015, 1: 35–37.

De Maeseneer MG, Kakkos SK, Aherne T, Baekgaard N, Black S, Blomgren L, et al. Editor’s Choice – European Society for Vascular Surgery (ESVS) 2022 Clinical Practice Guidelines on the Management of Chronic Venous Disease of the Lower Limbs. Eur J Vasc Endovasc Surg. 2022;63(2):184-267. https://doi.org/10.1016/j.ejvs.2021.12.024. Erratum in: Eur J Vasc Endovasc Surg. 2022;64(2-3):284-285.

Décousus H, Bertoletti L, Frappé P. Spontaneous acute superficial vein thrombosis of the legs: do we really need to treat? J Thromb Haemost. 2015;13 Suppl 1:S230-7. https://doi.org/10.1111/jth.12925

Di Minno MN, Ambrosino P, Ambrosini F, Tremoli E, Di Minno G, Dentali F. Prevalence of deep vein thrombosis and pulmonary embolism in patients with superficial vein thrombosis: a systematic review and meta-analysis. J Thromb Haemost. 2016;14(5):964-72. https://doi.org/10.1111/jth.13279

Levchak Yu. A. Diahnostyka ta likuvannia trombozu poverkhnevykh ven. Dodatok do kliniko-praktychnykh rekomendatsii «Khronichni zakhvoriuvannia ven nyzhnikh kintsivok i tazu.». Klinichna Khirurhiia. 2022 January/February; 89(1-2):72-77.

Popovich YaM. Profilaktyka tromboembolii lehenevoi arterii na tli transfastsialnoho trombozu [Profilaxis of pulmonary embolism with transfascial thrombosis]. Sertse i sudyny. 2018;61(1):58-64. Ukrainian. https:// doi.org/10.30978/HV2018158.

Popovych Ya.M., Korsak V.V., Boldizhar P.O., Laver O.P. Khronichna profilaktyka tromboembolichnykh uskladnen pry transfastsialnomu trombozi. Ukrainskyi zhurnal sertsevo-sudynnoi khirurhii. 2023, 31(1): 66–73.

Rusyn V.I., Boldizhar P.O., Horlenko F.V., Borsenko M.I. Ultrazvukova diahnostyka hostroho varykotromboflebitu. Naukovyi visnyk Uzhhorodskoho universytetu. Seriia Medytsyna. 2009. 37: 164–169.

Rusyn V.I., Korsak V.V., Boldizhar P.O., Krasnopolska O.S., Sirchak S.S., Lopit V.M. Venozna hemodynamika v umovakh hostroho varykotromboflebitu velykoi pidshkirnoi veny. Ukrainskyi zhurnal khirurhii. 2014. 2(25): 15–21.

Rusyn V.I., Korsak V.V., Boldizhar P.O., Levchak Yu.A., Borsenko M.I. Osoblyvosti flebohemodynamiky pry hostromu varykotromboflebiti Visnyk Vinnytskoho natsionalnoho medychnoho universytetu im. M.I. Pirohova. 2010. 14 (2): 242–246.

Usenko O. Yu., Chernukha L. M., Horbovets V. S., Hubka V. O., Hudz I.M., Hupalo Yu. M., ta in. Khronichni zakhvoriuvannia ven nyzhnikh kintsivok i tazu. Kliniko-praktychni rekomendatsii. Klinichna khirurhiia. 2022 January/February; 89(1-2):11-41. Ukrainian. https://doi.org/10.26779/2522-1396.2022.1-2.11

Werth S, Bauersachs R, Gerlach H, Rabe E, Schellong S, Beyer-WestendorfJ.Superficialveinthrombosis treatedfor 45 days with rivaroxaban versus fondaparinux: rationale and design of the SURPRISE trial. J Thromb Thrombolysis. 2016;42(2):197-204. https://doi.org/10.1007/s11239-016-1354-3

Published

2023-10-09

How to Cite

Корсак, В. В., Кочмарь, О. М., Горленко, Ф. В., & Попович, Я. М. (2023). Surgical prevention of pulmonary embolism in patients with lower extremities’ decompensated chronic venous insufficiency. Scientific Bulletin of the Uzhhorod University. Series «Medicine», (2(68), 57-62. https://doi.org/10.32782/2415-8127.2023.68.10

Issue

Section

GENERAL SURGERY (ALL SURGICAL DISCIPLINES)