Prophylaxis of pulmonary embolism with trombosis of the inferior vena cava

Authors

  • V.I. Rusyn Uzhhorod National University, Faculty of Medicine, Department of Surgical Diseases
  • V.V. Korsak Uzhhorod National University, Faculty of Medicine, Department of Surgical Diseases
  • Yа.M. Popovich Uzhhorod National University, Faculty of Medicine, Department of Surgical Diseases
  • S. O. Boiko Uzhhorod National University, Faculty of Medicine, Department of Surgical Diseases

DOI:

https://doi.org/10.24144/2415-8127.2018.57.86-91

Keywords:

deep vein thrombosis, inferior vena cava, pulmonary embolism, thrombectomy.

Abstract

The aim of research was to substantiate indices of surgical prophylactic of pulmonary embolism. Materials and methods. Has been analyzed the results of investigation and treatment in 790 patients with different forms deep thrombosis at inferior vena cava system. Patients were divided into the groups depending on the treatment. The first group consisted of 555 patients which performed the surgical treatment with the next conservative treatment. The first A group (n=380) consisted of patients which performed an open full or partial thrombectomy with or without surgical prophylactic of pulmonary thromboembolism. The first B group (n=50) consisted of patients which performed the combined treatment with surgical prophylactic of pulmonary thromboembolism. The first C group (n=125) consisted of patients which performed an operation with transfascial thrombosis. The second group (n=235) consisted of patients which performed only the conservative therapy. For investigation of patients were used the laboratory methods of examination, also the instrumental: ultrasound duplex scanning, X-ray phlebography, computer tomography and radionuclide fleboscintigraphy. During the radionuclide fleboscintigraphy at rest and during physical activity, the following indicators were determined: the average transport time of the radiopharmaceutical, the linear velocity of the blood and the loading index. Results. We offered the considerable attention to the definition of the variant of thrombotic lesion and the nature of thrombotic masses. The expansion of thrombotic occlusion is important for choosing the treatment method. The most patients – 441 (55,8%) – had lesion of one venous segment, the expansion of thrombotic masses in two venous segments founded in 167 (21,1%) patients, the lesion more than two venous segments observed in 182 (23,1%) of cases. Evaluated the upper and lower boundaries of thrombotic masses. The transition of thrombotic process from the superficial venous system to the deep caused the real threat of pulmonary embolism, in particular, in all 125 (100,0%) patients first C group, discovered the floating top of the thrombotic masses.The cumulative analysis the results of the treatment patients with thrombosis of inferior vena cava system during 3 years of follow-up showed that good and satisfactory results in the first A group were observed in 89,3%, in the first B group – 81,7%, in the first C group – 88, 4% and in the second group – 35,3% of patients. Conclusion. When choosing the indices for surgical treatment of thrombosis the inferior vena cava system, should be given to the cause of thrombosis, the nature of thrombotic masses, the variant and the spread of thrombotic lesion, the presence of flotation the top of thrombotic masses. The offered medical-diagnostic algorithm allows to effectively prevent the pulmonary embolism.

References

Konstantinides SV, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Galie N, et al. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) Endorsed by the European Respiratory Society (ERS). European heart journal. 2014;35(43):3033–69.

Prevention and treatment of venous thromboembolism. International Consensus Statement (Guidelines according to scientific evidence). International angiology. April 2013;32(2):256.

Boiko VN, Bereznytskyi YaS, Venher IK, et al. Venoznyi tromboembolizm: diahnostyka, likuvannia, profilaktyka. Mizhdystsyplinarni klinichni rekomendatsii: naukove vydannia. Kyiv; 2013.63 s. [In Ukrainian].

Kyryenko AY, Cherniavskoho AM, Andryiashkyna VV, editors. Tromboembolyia lehochnykh arteryi. Kak lechyt y predotvrashchat: monohrafyia. Moskva: OOO Yzdatelstvo «Medytsynskoe ynformatsyonnoe ahenstvo»; 2015. 280 s. [In Russian].

Denysiuk VI, Denysiuk OV. Tromboemboliia lehenevoi arterii: standarty diahnostyky, likuvannia ta profilaktyky zghidno z rekomendatsiiamy dokazovoi medytsyny. Praktychna anhiolohiia. 2010;2(31):64–70. [In Ukrainian].

Zhane AK, Voskanian YuЕ, Holubov EA. Analyz khyrurhycheskoi profylaktyky tromboembolyy lehochnykh arteryi mnohoprofylnoho statsyonara. Kubanskyi nauchnyi medytsynskyi vestnyk. 2013;4(139):45-7. [In Russian].

Matviichuk BO, Fedchyshyn NR, Matviichuk OB. Venozni trombozy ta embolii: suchasni osoblyvosti profilaktyky v zahalnii khirurhii. Khirurhiia Ukrainy. 2010;2(34):81-4. [In Ukrainian]. 8. Boiko VN, Bereznytskyi YaS, Venher IK, et al. Ukrainski mizhdystsyplinarni klinichni rekomendatsii po profilaktytsi, diahnostytsi ta likuvanniu venoznykh tromboembolichnykh uskladnen. Klinichna flebolohiia. 2017;10(1):42–104. [In Ukrainian].

Kearon C, Akl EA, Ornelas J, Blaivas A, Jimenez D, Bounameaux H, et al. Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (10th Edition). Chest. 2016;149(2):315-52.

Meissner MH, Gloviczki P, Comerota AJ, Dalsing MC, Eklof BG, Gillespie DL, et al. Early thrombus removal strategies for acute deep venous thrombosis: Clinical Practice Guidelines of the Society for Vascular Surgery and the American Venous Forum. J. Vasc. Surgery. 2012;55:1449-62.

Published

2022-05-12

How to Cite

Русин, В. ., Корсак, В. ., Попович, Я. ., & Бойко, С. . (2022). Prophylaxis of pulmonary embolism with trombosis of the inferior vena cava. Scientific Bulletin of the Uzhhorod University. Series «Medicine», (1 (57), 86-91. https://doi.org/10.24144/2415-8127.2018.57.86-91

Most read articles by the same author(s)