Features of the course of covid -19 in children of southern ukraine (experience of the winter season 2021-2022)
DOI:
https://doi.org/10.32782/2415-8127.2022.66.19Keywords:
children, coronavirus infection, respiratory pathology, symptoms, clinical signs.Abstract
Introduction. The infection caused by the SARS-CoV-2 virus can have different clinical manifestations, affect both the respiratory system and other organ systems, and the course can vary from asymptomatic or mild to severe, requiring hospitalization. The diversity of clinical manifestations of the disease, the peculiarities of the course of the disease in different age periods force doctors to be attentive to any symptoms in patients, both those related to the respiratory system and atypical complaints. Any new information about the peculiarities of the course of the coronavirus infection, age differences, "masks" of the disease, typical and atypical clinical manifestations is important. Purpose of research. The purpose of the study was to study and analyze the clinical features of the course of the disease COVID-19 in children in the winter season of 2021-22. Materials and methods. Retrospective analysis of the disease histories of children with a severe course of COVID-19 was carried out. Results. School-age children predominated among those hospitalized, which emphasizes the epidemiological significance of this particular age category in implementation of timely quarantine measures in educational institutions. Among the clinical manifestations, both typical signs of damage to the respiratory system and symptoms of damage from the gastrointestinal tract were registered. A characteristic feature of the course of COVID-19 in the specified winter season of 2021-22. a mixed infection with rotavirus and influenza was registered, which was not observed during the previous wave of the disease. Conclusions. The identified features of the course of COVID-19 in children will help to improve algorithms for providing assistance to
patients of different age categories and predict the course of the disease.
References
VOZ. Naymenovanye zabolevanyya, vyzvannogo koronavyrusom (COVID-19), y vyrusnogo vozbudytelya [Name of the disease caused by the coronavirus (CHOVID-19) and the viral pathogen]. [Russian]. 2020. Available from: https://www.who. int/ru/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-andthe- virus-that-causes-it
Country & Technical Guidance – Coronavirus disease (COVID-19). Available from: https://www.who.int/emergencies/ diseases/novel-coronavirus-2019/technical-guidance
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novelcoronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020 Feb 15; 395(10223): 507-513. doi: 10.1016/ S0140-6736(20)30211-7
Global Surveillance for human infection with coronavirus disease (COVID-19) Interim guidance 27 February 2020. Available from: https://www.who.int/publications-detail/global-surveillance-for-human-infection-with-novel-coronavirus-(2019-ncov)
Wang W, Tang J, Wei F, Wang W. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J Med Virol. 2020; 92(4): 441-447. doi: 10.1002/jmv.25689
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020 Mar 17; 323(11): 1061-1069. doi: 10.1001/jama.2020.1585
Fei Zhou, Ting Yu, Ronghui Du, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. Published Online March 9, 2020 https://doi.org/10.1016/ S0140–6736(20)30566–3
Guan W, Ni Z, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. DOI: 10.1056/ NEJMoa2002032.
An update on the epidemiological characteristics of novel coronavirus pneumonia (COVID-19). Special Expert Group for Control of the Epidemic of Novel Coronavirus Pneumonia of the Chinese Preventive Medicine Association. Zhonghua Liu Xing Bing XueZa Zhi. 2020; 41(2): 139-144. doi: 10.3760/cma.j.is sn.0254-6450.2020.02.002
Nakaz No722 Ministerstva okhorony zdorov’ya Ukrayiny vid 28.03.2020. Organizatsiya nadannya medychnoyi dopomogy khvorym na koronavirusnu khvorobu COVID -19 [Organization of medical aid for COVID-19 ailments for coronavirus disease]. 2020. [Ukrainian]
