Assessment of the influence of the method of anesthesia on the degree of postoperative pain in patients with colon cancer
Keywords:
epidural anesthesia, pain syndrome, stress markers.Abstract
The aim of the study. Depending on the chosen method of anesthesia to assess the degree of postoperative pain in patients with colon cancer. Materials and methods. In the period from January to August 2020, an analysis of the results of anesthesia in 32 patients with colon cancer was performed on the basis of the Department of Anesthesiology and Intensive Care of «TOC». Two groups of patients were formed in a randomized manner. The difference between the groups was the difference in drug combinations and dosages of anesthesia. In order to objectify the level of pain, changes in hemodynamic and biochemical parameters were studied. values, and statistically significant was considered the level of p <0,05. Results. There was a statistically significant difference in the results of changes in vital functions between groups I and II in all indicators in the postoperative period after 6 hours, which characterizes the fact of more effective reduction of pain when using general anesthesia in combination with epidural anesthesia (p = 0.0001). After evaluating the results of biochemical markers of pain, it was found that between group I and II before surgery, a statistically significant difference is observed in the level of cortisol. Significant changes in cortisol levels after surgery in patients of groups I and II (p = 0.0001). When comparing insulin and blood glucose, the results of biochemical parameters were lower in group II patients, indicating a lower level of pain or its absence in the first 6 hours after surgery (p = 0.0001). When comparing the results of the pain questionnaire for patients with colon cancer before and after surgery, a statistically significant difference in the level of pain (p=0.0001).
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