The frequency of Helicobacter pylori infection in the lesion of esophagogastroduodenal zone in patients with spinal osteochondrosis

Abstract

Introduction. An important component of the treatment of spinal degenerative disc disease (DDD) is the prevention of degenerative processes in articular cartilage, reduction of pain and inflammation. Current guidelines recommend testing and treating H. pylori (HP) infection in patients taking NSAIDs who are at risk of upper gastrointestinal bleeding. The purpose of the study: to determine the frequency of Helicobacter pylori (HP) infection in the lesion of esophagogastroduodenal zone (EGDZ) in patients with osteochondrosis (OC of the lumbar spine). Object and research methods. We examined 226 patients with OC of the lumbar spine and EGDZ lesions. Patients were divided into three groups, depending on the endoscopic findings of upper gastrointestinal tract lesions: group I included patients with gastroesophageal reflux disease (GERD) (n=78); group II included patients with chronic gastritis (CG) (n=102); group III included patients with gastric ulcer (GU) and duodenal ulcer (DU) (n=46). All examined patients were diagnosed with HP infection. Research results and their discussion. A high incidence of HP infection in patients with EGDZ and OC of the lumbar spine was found (88.9 % of patients). At the same time, HP infection was diagnosed more often in patients of group III (with gastric and duodenal ulcers) – 95.7 % of cases, as well as in patients of group II with CG – 90.2 % of the examined. In patients of group I with GERD and OC of the lumbar spine, HP was diagnosed in only 83.3 % of patients (p<0.05). According to the results obtained, regardless of the form of EGDZ lesions in the examined patients with OC of the lumbar spine, clinically, EGDZ lesions are more pronounced in the case of persistent HP infection. Conclusions. 1. A high incidence of HP infection (88.9 % of cases) was found in patients with OC of the lumbar spine and EGDZ lesions, with these patients being mainly those with gastric and duodenal ulcers (95.7 % of cases). 2. In HP-positive patients with OC of the lumbar spine and EGDZ lesions, clinical symptoms are more pronounced regardless of the form of upper gastrointestinal lesions, manifested by heartburn, acid belching, pain and heaviness in the epigastric region, as well as periodic nausea and vomiting against a background of decreased appetite.